Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA4958
|
Name |
fimW
|
Replicon | chromosome |
Genomic location | 5563605 - 5565428 (+ strand) |
Transposon Mutants | 3 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 3 transposon mutants in orthologs |
Comment | A pilZ domain starting at amino acid 323 and stopping at amino acid 492 was manually validated |
Comment | FimW is a cyclic-di-GMP receptor that regulates Type IV pili elongation. |
Comment | Site-directed mutagenesis demonstrated that the ligand (cyclic-di-GMP) binding motif is R324, R328, N435, S437, G440. |
RefSeq | NP_253645.1 |
GI | 15600151 |
Affymetrix | PA4958_at |
Entrez | 878415 |
GenBank | AAG08343.1 |
INSDC | AAG08343.1 |
NCBI Locus Tag | PA4958 |
protein_id(GenBank) | gb|AAG08343.1|AE004908_9|gnl|PseudoCAP|PA4958 |
TIGR | NTL03PA04959 |
UniParc | UPI00000C5E95 |
UniProtKB Acc | Q9HUK7 |
UniProtKB ID | Q9HUK7_PSEAE |
UniRef100 | UniRef100_Q9HUK7 |
UniRef50 | UniRef50_Q9HUK7 |
UniRef90 | UniRef90_Q9HUK7 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
FimW
|
Synonyms | |
Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
Charge (pH 7) | 2.80 |
Kyte-Doolittle Hydrophobicity Value | -0.249 |
Molecular Weight (kDa) | 67.8 |
Isoelectric Point (pI) | 7.42 |
Individual Mappings | |
Additional evidence for subcellular localization |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 24 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG004573 (412 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA4958
Search term: fimW
Search term: FimW
|
A Surface-Induced Asymmetric Program Promotes Tissue Colonization by Pseudomonas aeruginosa.
Laventie BJ, Sangermani M, Estermann F, Manfredi P, Planes R, Hug I, Jaeger T, Meunier E, Broz P, Jenal U
Cell Host Microbe 2019 Jan 9;25(1):140-152.e6
PubMed ID: 30581112
|