Pseudomonas aeruginosa PAO1, PA4978

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4978
Name
Replicon chromosome
Genomic location 5589295 - 5591385 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_253665.1
GI 15600171
Affymetrix PA4978_at
Entrez 880190
GenBank AAG08363.1
INSDC AAG08363.1
NCBI Locus Tag PA4978
protein_id(GenBank) gb|AAG08363.1|AE004910_10|gnl|PseudoCAP|PA4978
TIGR NTL03PA04979
UniParc UPI00000C5EA7
UniProtKB Acc Q9HUI7
UniProtKB ID Q9HUI7_PSEAE
UniRef100 UniRef100_Q9HUI7
UniRef50 UniRef50_K9NL67
UniRef90 UniRef90_A0A077JZT8

Product

Feature Type CDS
Coding Frame 1
Product Name
hypothetical protein
Product Name Confidence: Class 4
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -11.44
Kyte-Doolittle Hydrophobicity Value 0.259
Molecular Weight (kDa) 72.6
Isoelectric Point (pI) 5.43

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 359 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004592 (371 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4978

Human Homologs

References

Purification, characterization, DNA sequence and cloning of a pimeloyl-CoA synthetase from Pseudomonas mendocina 35.
Binieda A, Fuhrmann M, Lehner B, Rey-Berthod C, Frutiger-Hughes S, Hughes G, Shaw NM
Biochem J 1999 Jun 15;340 ( Pt 3)(Pt 3):793-801
PubMed ID: 10359666