Pseudomonas aeruginosa PAO1, PA5031

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA5031
Name
Replicon chromosome
Genomic location 5661701 - 5662630 (- strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_253718.1
GI 15600224
Affymetrix PA5031_at
Entrez 881213
GenBank AAG08416.1
INSDC AAG08416.1
NCBI Locus Tag PA5031
protein_id(GenBank) gb|AAG08416.1|AE004916_5|gnl|PseudoCAP|PA5031
TIGR NTL03PA05032
UniParc UPI00000C5ED6
UniProtKB Acc Q9HUD8
UniProtKB ID Q9HUD8_PSEAE
UniRef100 UniRef100_Q9HUD8
UniRef50 UniRef50_C6WEP6
UniRef90 UniRef90_Q9HUD8

Product

Feature Type CDS
Coding Frame 1
Product Name
probable short chain dehydrogenase
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Charge (pH 7) 15.34
Kyte-Doolittle Hydrophobicity Value -0.202
Molecular Weight (kDa) 34.0
Isoelectric Point (pI) 10.85

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 564 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004636 (321 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5031

Human Homologs

Ensembl 110, assembly GRCh38.p14
retinol dehydrogenase 13 [Source:HGNC Symbol;Acc:HGNC:19978]
E-value: 4.2e-41
Percent Identity: 39.5
Ensembl 110, assembly GRCh38.p14
retinol dehydrogenase 13 [Source:HGNC Symbol;Acc:HGNC:19978]
E-value: 4.2e-41
Percent Identity: 39.5

References

An integrated map of the genome of the tubercle bacillus, Mycobacterium tuberculosis H37Rv, and comparison with Mycobacterium leprae.
Philipp WJ, Poulet S, Eiglmeier K, Pascopella L, Balasubramanian V, Heym B, Bergh S, Bloom BR, Jacobs WR Jr, Cole ST
Proc Natl Acad Sci U S A 1996 Apr 2;93(7):3132-7
PubMed ID: 8610181