Pseudomonas aeruginosa PAO1, PA5033

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA5033
Name
Replicon chromosome
Genomic location 5663889 - 5664869 (+ strand)
Transposon Mutants 6 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_253720.1
GI 15600226
Affymetrix PA5033_at
DNASU PaCD00008168
Entrez 881201
GenBank AAG08418.1
INSDC AAG08418.1
NCBI Locus Tag PA5033
protein_id(GenBank) gb|AAG08418.1|AE004916_7|gnl|PseudoCAP|PA5033
TIGR NTL03PA05034
UniParc UPI00000C5ED8
UniProtKB Acc Q9HUD6
UniProtKB ID Q9HUD6_PSEAE
UniRef100 UniRef100_Q9HUD6
UniRef50 UniRef50_Q9HUD6
UniRef90 UniRef90_Q9HUD6

Product

Feature Type CDS
Coding Frame 1
Product Name
hypothetical protein
Product Name Confidence: Class 4
Synonyms
Evidence for Translation
Charge (pH 7) -4.10
Kyte-Doolittle Hydrophobicity Value -0.062
Molecular Weight (kDa) 34.2
Isoelectric Point (pI) 5.37

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
mass spectrometry evidence used in manual assertion
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 3 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004638 (300 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5033

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Mep72, a metzincin protease that is preferentially secreted by biofilms of Pseudomonas aeruginosa.
Passmore IJ, Nishikawa K, Lilley KS, Bowden SD, Chung JC, Welch M
J Bacteriol 2015 Feb 15;197(4):762-73
PubMed ID: 25488299