Pseudomonas aeruginosa PAO1, PA5133

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA5133
Name
Synonym: yibP
Replicon chromosome
Genomic location 5780963 - 5782249 (+ strand)
Transposon Mutants 1 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_253820.1
GI 15600326
Affymetrix PA5133_at
Entrez 878609
GenBank AAG08518.1
INSDC AAG08518.1
NCBI Locus Tag PA5133
protein_id(GenBank) gb|AAG08518.1|AE004926_8|gnl|PseudoCAP|PA5133
TIGR NTL03PA05134
UniParc UPI00000C5F1B
UniProtKB Acc Q9HU51
UniProtKB ID Q9HU51_PSEAE
UniRef100 UniRef100_Q9HU51
UniRef50 UniRef50_G8Q1I7
UniRef90 UniRef90_Q9HU51

Product

Feature Type CDS
Coding Frame 1
Product Name
conserved hypothetical protein
Product Name Confidence: Class 4
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 11.16
Kyte-Doolittle Hydrophobicity Value -0.691
Molecular Weight (kDa) 47.3
Isoelectric Point (pI) 9.91

Subcellular localization

Individual Mappings
Localization Confidence PMID
Outer Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
8I6O MEMBRANE PROTEIN 01/29/23 Cryo-EM structure of Pseudomonas aeruginosa FtsE(WT)X/EnvC complex in peptidisc Pseudomonas aeruginosa 3.8 ELECTRON MICROSCOPY 98.5
8I6S MEMBRANE PROTEIN 01/29/23 Cryo-EM structure of Pseudomonas aeruginosa FtsE(E163Q)X/EnvC complex with ATP in peptidisc Pseudomonas aeruginosa 4.4 ELECTRON MICROSCOPY 98.5

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 504 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004725 (530 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5133

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295