Pseudomonas aeruginosa PAO1, PA5152

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA5152
Name
Replicon chromosome
Genomic location 5800527 - 5801300 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_253839.1
GI 15600345
Affymetrix PA5152_at
Entrez 879975
GenBank AAG08537.1
INSDC AAG08537.1
NCBI Locus Tag PA5152
protein_id(GenBank) gb|AAG08537.1|AE004928_3|gnl|PseudoCAP|PA5152
TIGR NTL03PA05153
UniParc UPI00000C5F2A
UniProtKB Acc Q9HU32
UniProtKB ID Q9HU32_PSEAE
UniRef100 UniRef100_W0YYS4
UniRef50 UniRef50_D7I6D4
UniRef90 UniRef90_W6RL63

Product

Feature Type CDS
Coding Frame 1
Product Name
probable ATP-binding component of ABC transporter
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 0.63
Kyte-Doolittle Hydrophobicity Value -0.224
Molecular Weight (kDa) 28.4
Isoelectric Point (pI) 7.22

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 2
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 669 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004745 (526 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5152

Human Homologs

Ensembl 110, assembly GRCh38.p14
ATP binding cassette subfamily B member 4 [Source:HGNC Symbol;Acc:HGNC:45]
E-value: 1.2e-22
Percent Identity: 31.4
Ensembl 110, assembly GRCh38.p14
ATP binding cassette subfamily B member 4 [Source:HGNC Symbol;Acc:HGNC:45]
E-value: 1.2e-22
Percent Identity: 31.4
Ensembl 110, assembly GRCh38.p14
ATP binding cassette subfamily B member 4 [Source:HGNC Symbol;Acc:HGNC:45]
E-value: 1.2e-22
Percent Identity: 31.4
Ensembl 110, assembly GRCh38.p14
ATP binding cassette subfamily B member 4 [Source:HGNC Symbol;Acc:HGNC:45]
E-value: 1.2e-22
Percent Identity: 31.4

References

Opine transport genes in the octopine (occ) and nopaline (noc) catabolic regions in Ti plasmids of Agrobacterium tumefaciens.
Zanker H, von Lintig J, Schröder J
J Bacteriol 1992 Feb;174(3):841-9
PubMed ID: 1732218