Pseudomonas aeruginosa PAO1, PA5166 (dctD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA5166
Name
dctD
Replicon chromosome
Genomic location 5815562 - 5816950 (+ strand)
Transposon Mutants 4 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_253853.1
GI 15600359
Affymetrix PA5166_at
Entrez 879963
GenBank AAG08551.1
INSDC AAG08551.1
NCBI Locus Tag PA5166
protein_id(GenBank) gb|AAG08551.1|AE004929_6|gnl|PseudoCAP|PA5166
TIGR NTL03PA05167
UniParc UPI00000C5F33
UniProtKB Acc Q9HU19
UniProtKB ID Q9HU19_PSEAE
UniRef100 UniRef100_W0YYT8
UniRef50 UniRef50_A9CEZ3
UniRef90 UniRef90_W0YYT8

Product

Feature Type CDS
Coding Frame 1
Product Name
DctD
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -10.87
Kyte-Doolittle Hydrophobicity Value -0.244
Molecular Weight (kDa) 50.9
Isoelectric Point (pI) 5.50

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 1
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 623 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004757 (532 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5166
Search term: dctD
Search term: DctD

Human Homologs

References

Identification of C(4)-dicarboxylate transport systems in Pseudomonas aeruginosa PAO1.
Valentini M, Storelli N, Lapouge K
J Bacteriol 2011 Sep;193(17):4307-16
PubMed ID: 21725012