Pseudomonas aeruginosa PAO1, PA5180

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA5180
Name
Synonym: fdhD
Replicon chromosome
Genomic location 5831902 - 5832741 (+ strand)
Transposon Mutants 4 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_253867.1
GI 15600373
Affymetrix PA5180_at
DNASU PaCD00008229
Entrez 881723
GenBank AAG08565.1
INSDC AAG08565.1
NCBI Locus Tag PA5180
protein_id(GenBank) gb|AAG08565.1|AE004931_2|gnl|PseudoCAP|PA5180
TIGR NTL03PA05181
UniParc UPI00000C5F3D
UniProtKB Acc Q9HU09
UniProtKB ID Q9HU09_PSEAE
UniRef100 UniRef100_Q9HU09
UniRef50 UniRef50_Q4KAA7
UniRef90 UniRef90_Q02EI5

Product

Feature Type CDS
Coding Frame 1
Product Name
conserved hypothetical protein
Product Name Confidence: Class 4
Synonyms
Evidence for Translation
Charge (pH 7) -0.09
Kyte-Doolittle Hydrophobicity Value -0.182
Molecular Weight (kDa) 30.2
Isoelectric Point (pI) 6.99

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 344 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004768 (530 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5180

Human Homologs

References

Structural analysis of the fds operon encoding the NAD+-linked formate dehydrogenase of Ralstonia eutropha.
Oh JI, Bowien B
J Biol Chem 1998 Oct 9;273(41):26349-60
PubMed ID: 9756865