Pseudomonas aeruginosa PAO1, PA5181

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA5181
Name
Replicon chromosome
Genomic location 5832749 - 5835070 (+ strand)
Transposon Mutants 6 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_253868.1
GI 15600374
Affymetrix PA5181_at
Entrez 881731
GenBank AAG08566.1
INSDC AAG08566.1
NCBI Locus Tag PA5181
protein_id(GenBank) gb|AAG08566.1|AE004931_3|gnl|PseudoCAP|PA5181
TIGR NTL03PA05182
UniParc UPI00000C5F3E
UniProtKB Acc Q9HU08
UniProtKB ID Q9HU08_PSEAE
UniRef100 UniRef100_Q9HU08
UniRef50 UniRef50_P9WJP8
UniRef90 UniRef90_Q9HU08

Product

Feature Type CDS
Coding Frame 1
Product Name
probable oxidoreductase
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Charge (pH 7) 0.51
Kyte-Doolittle Hydrophobicity Value -0.338
Molecular Weight (kDa) 85.3
Isoelectric Point (pI) 7.05

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 458 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004769 (523 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5181

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Analysis of the genes forming the distal parts of the two cbb CO2 fixation operons from Alcaligenes eutrophus.
Schäferjohann J, Yoo JG, Bowien B
Arch Microbiol 1995 Apr;163(4):291-9
PubMed ID: 7763137
Identification of cbbBc as an additional distal gene of the chromosomal cbb CO2 fixation operon from Ralstonia eutropha.
Bömmer D, Schäferjohann J, Bowien B
Arch Microbiol 1996 Oct;166(4):245-51
PubMed ID: 8824147