Pseudomonas aeruginosa PAO1, PA5186

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA5186
Name
Replicon chromosome
Genomic location 5837915 - 5839078 (- strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 3 transposon mutants in orthologs

Cross-References

RefSeq NP_253873.1
GI 15600379
Affymetrix PA5186_at
Entrez 881522
GenBank AAG08571.1
INSDC AAG08571.1
NCBI Locus Tag PA5186
protein_id(GenBank) gb|AAG08571.1|AE004931_8|gnl|PseudoCAP|PA5186
TIGR NTL03PA05187
UniParc UPI00000C5F42
UniProtKB Acc Q9HU03
UniProtKB ID Q9HU03_PSEAE
UniRef100 UniRef100_U9IHV3
UniRef50 UniRef50_A9HYQ4
UniRef90 UniRef90_A0A022P1E8

Product

Feature Type CDS
Coding Frame 1
Product Name
probable iron-containing alcohol dehydrogenase
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -6.40
Kyte-Doolittle Hydrophobicity Value 0.282
Molecular Weight (kDa) 40.4
Isoelectric Point (pI) 5.42

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 1
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 481 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001106 (1358 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5186

Human Homologs

Ensembl 110, assembly GRCh38.p14
alcohol dehydrogenase iron containing 1 [Source:HGNC Symbol;Acc:HGNC:16354]
E-value: 1.1e-35
Percent Identity: 32.1
Ensembl 110, assembly GRCh38.p14
alcohol dehydrogenase iron containing 1 [Source:HGNC Symbol;Acc:HGNC:16354]
E-value: 1.1e-35
Percent Identity: 32.1

References

No references are associated with this feature.