Pseudomonas aeruginosa PAO1, PA5193 (yrfI)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA5193
Name
yrfI
Replicon chromosome
Genomic location 5846125 - 5847018 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_253880.1
GI 15600386
Affymetrix PA5193_yrfI_at
DNASU PaCD00008235
Entrez 879313
GenBank AAG08578.1
INSDC AAG08578.1
NCBI Locus Tag PA5193
protein_id(GenBank) gb|AAG08578.1|AE004932_5|gnl|PseudoCAP|PA5193
TIGR NTL03PA05194
UniParc UPI000012CD06
UniProtKB Acc Q9HTZ6
UniProtKB ID HSLO_PSEAE
UniRef100 UniRef100_B7V3U0
UniRef50 UniRef50_Q4KK04
UniRef90 UniRef90_B7V3U0

Product

Feature Type CDS
Coding Frame 1
Product Name
heat shock protein HSP33
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -17.55
Kyte-Doolittle Hydrophobicity Value -0.228
Molecular Weight (kDa) 32.8
Isoelectric Point (pI) 4.46

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 335 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004777 (535 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5193
Search term: yrfI

Human Homologs

References

Chaperone activity with a redox switch.
Jakob U, Muse W, Eser M, Bardwell JC
Cell 1999 Feb 5;96(3):341-52
PubMed ID: 10025400