Pseudomonas aeruginosa PAO1, PA5200 (amgR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA5200
Name
amgR
Replicon chromosome
Genomic location 5852653 - 5853396 (- strand)
Transposon Mutants 1 transposon mutants in PAO1

Cross-References

RefSeq NP_253887.1
GI 15600393
Affymetrix PA5200_ompR_at
DNASU PaCD00008239
Entrez 880301
GenBank AAG08585.1
INSDC AAG08585.1
NCBI Locus Tag PA5200
protein_id(GenBank) gb|AAG08585.1|AE004933_1|gnl|PseudoCAP|PA5200
TIGR NTL03PA05201
UniParc UPI00000C5F4E
UniProtKB Acc Q9HTY9
UniProtKB ID Q9HTY9_PSEAE
UniRef100 UniRef100_W0Z312
UniRef50 UniRef50_Q3IJP0
UniRef90 UniRef90_A4VG91

Product

Feature Type CDS
Coding Frame 1
Product Name
AmgR
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -0.54
Kyte-Doolittle Hydrophobicity Value -0.331
Molecular Weight (kDa) 27.9
Isoelectric Point (pI) 6.57

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 2
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 626 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004784 (536 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5200
Search term: amgR
Search term: AmgR

Human Homologs

References

Primary characterization of the protein products of the Escherichia coli ompB locus: structure and regulation of synthesis of the OmpR and EnvZ proteins.
Comeau DE, Ikenaka K, Tsung KL, Inouye M
J Bacteriol 1985 Nov;164(2):578-84
PubMed ID: 2997120
The DNA-binding domain of OmpR: crystal structures of a winged helix transcription factor.
Martínez-Hackert E, Stock AM
Structure 1997 Jan 15;5(1):109-24
PubMed ID: 9016718
Targeting a bacterial stress response to enhance antibiotic action.
Lee S, Hinz A, Bauerle E, Angermeyer A, Juhaszova K, Kaneko Y, Singh PK, Manoil C
Proc Natl Acad Sci U S A 2009 Aug 25;106(34):14570-5
PubMed ID: 19706543