Pseudomonas aeruginosa PAO1, PA5216

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA5216
Name
Replicon chromosome
Genomic location 5872900 - 5874519 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_253903.1
GI 15600409
Affymetrix PA5216_at
Entrez 880841
GenBank AAG08601.1
INSDC AAG08601.1
NCBI Locus Tag PA5216
protein_id(GenBank) gb|AAG08601.1|AE004934_8|gnl|PseudoCAP|PA5216
TIGR NTL03PA05217
UniParc UPI00000C5F5A
UniProtKB Acc Q9HTX4
UniProtKB ID Q9HTX4_PSEAE
UniRef100 UniRef100_S0HVE8
UniRef50 UniRef50_G8Q4U5
UniRef90 UniRef90_A6VDZ2

Product

Feature Type CDS
Coding Frame 1
Product Name
probable permease of ABC iron transporter
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 17.55
Kyte-Doolittle Hydrophobicity Value 0.790
Molecular Weight (kDa) 58.5
Isoelectric Point (pI) 10.40

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 2
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 479 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004798 (529 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5216

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Nucleotide sequences of the sfuA, sfuB, and sfuC genes of Serratia marcescens suggest a periplasmic-binding-protein-dependent iron transport mechanism.
Angerer A, Gaisser S, Braun V
J Bacteriol 1990 Feb;172(2):572-8
PubMed ID: 2404942