Pseudomonas aeruginosa PAO1, PA5298

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA5298
Name
Synonym: xpt
Replicon chromosome
Genomic location 5966706 - 5967278 (+ strand)
Transposon Mutants 1 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_253985.1
GI 15600491
Affymetrix PA5298_at
Entrez 878159
GenBank AAG08683.1
INSDC AAG08683.1
NCBI Locus Tag PA5298
protein_id(GenBank) gb|AAG08683.1|AE004942_6|gnl|PseudoCAP|PA5298
TIGR NTL03PA05299
UniParc UPI00000C5F93
UniProtKB Acc Q9HTQ6
UniProtKB ID XPT_PSEAE
UniRef100 UniRef100_Q9HTQ6
UniRef50 UniRef50_P42085
UniRef90 UniRef90_Q9HTQ6

Product

Feature Type CDS
Coding Frame 1
Product Name
xanthine phosphoribosyltransferase
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -1.32
Kyte-Doolittle Hydrophobicity Value 0.201
Molecular Weight (kDa) 20.6
Isoelectric Point (pI) 6.64

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 274 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004872 (532 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5298

Human Homologs

References

Xanthine metabolism in Bacillus subtilis: characterization of the xpt-pbuX operon and evidence for purine- and nitrogen-controlled expression of genes involved in xanthine salvage and catabolism.
Christiansen LC, Schou S, Nygaard P, Saxild HH
J Bacteriol 1997 Apr;179(8):2540-50
PubMed ID: 9098051