Pseudomonas aeruginosa PAO1, PA5303

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA5303
Name
Replicon chromosome
Genomic location 5971850 - 5972203 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 3 transposon mutants in orthologs

Cross-References

RefSeq NP_253990.1
GI 15600496
Affymetrix PA5303_at
DNASU PaCD00008290
Entrez 878056
GenBank AAG08688.1
INSDC AAG08688.1
NCBI Locus Tag PA5303
protein_id(GenBank) gb|AAG08688.1|AE004943_4|gnl|PseudoCAP|PA5303
TIGR NTL03PA05304
UniParc UPI00000C5F97
UniProtKB Acc Q9HTQ1
UniProtKB ID Q9HTQ1_PSEAE
UniRef100 UniRef100_W0Z259
UniRef50 UniRef50_Q4K3T8
UniRef90 UniRef90_W0Z259

Product

Feature Type CDS
Coding Frame 1
Product Name
conserved hypothetical protein
Product Name Confidence: Class 4
Synonyms
Evidence for Translation
Detected by iTRAQ (PMID:21863142).
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -6.56
Kyte-Doolittle Hydrophobicity Value -0.169
Molecular Weight (kDa) 13.0
Isoelectric Point (pI) 4.47

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 427 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001525 (1734 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5303

Human Homologs

References

Comparisons of Two Proteomic Analyses of Non-Mucoid and Mucoid Pseudomonas aeruginosa Clinical Isolates from a Cystic Fibrosis Patient.
Rao J, Damron FH, Basler M, Digiandomenico A, Sherman NE, Fox JW, Mekalanos JJ, Goldberg JB
Front Microbiol 2011;2:162
PubMed ID: 21863142