Pseudomonas aeruginosa PAO1, PA5319 (radC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA5319
Name
radC
Replicon chromosome
Genomic location 5988646 - 5989320 (- strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_254006.1
GI 15600512
Affymetrix PA5319_radC_at
DNASU PaCD00008296
Entrez 877886
GenBank AAG08704.1
INSDC AAG08704.1
NCBI Locus Tag PA5319
protein_id(GenBank) gb|AAG08704.1|AE004944_8|gnl|PseudoCAP|PA5319
TIGR NTL03PA05320
UniParc UPI00001330C0
UniProtKB Acc Q9HTN5
UniProtKB ID Y5319_PSEAE
UniRef100 UniRef100_Q9HTN5
UniRef50 UniRef50_Q12EY8
UniRef90 UniRef90_Q9HTN5

Product

Feature Type CDS
Coding Frame 1
Product Name
DNA repair protein RadC
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) 1.07
Kyte-Doolittle Hydrophobicity Value -0.039
Molecular Weight (kDa) 24.9
Isoelectric Point (pI) 7.31

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 475 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004890 (535 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5319
Search term: radC

Human Homologs

References

Molecular cloning and DNA sequencing of the radC gene of Escherichia coli K-12.
Felzenszwalb I, Boiteux S, Laval J
Mutat Res 1992 May;273(3):263-9
PubMed ID: 1374847
Cloning of the Escherichia coli radC gene: identification of the RadC protein.
Felzenszwalb I, Boiteux S, Laval J
Braz J Med Biol Res 1993 Dec;26(12):1261-8
PubMed ID: 8136727
Tandem repeat recombination induced by replication fork defects in Escherichia coli requires a novel factor, RadC.
Saveson CJ, Lovett ST
Genetics 1999 May;152(1):5-13
PubMed ID: 10224240