Pseudomonas aeruginosa PAO1, PA5339

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA5339
Name
Replicon chromosome
Genomic location 6008398 - 6008778 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_254026.1
GI 15600532
Affymetrix PA5339_at
DNASU PaCD00008308
Entrez 877913
GenBank AAG08724.1
INSDC AAG08724.1
NCBI Locus Tag PA5339
protein_id(GenBank) gb|AAG08724.1|AE004946_8|gnl|PseudoCAP|PA5339
TIGR NTL03PA05340
UniParc UPI00000C5FAF
UniProtKB Acc Q9HTL9
UniProtKB ID Q9HTL9_PSEAE
UniRef100 UniRef100_W0Z0B5
UniRef50 UniRef50_O66689
UniRef90 UniRef90_A6VEE6

Product

Feature Type CDS
Coding Frame 1
Product Name
conserved hypothetical protein
Product Name Confidence: Class 4
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Detected by iTRAQ (PMID:21863142).
Charge (pH 7) -4.29
Kyte-Doolittle Hydrophobicity Value 0.136
Molecular Weight (kDa) 13.6
Isoelectric Point (pI) 4.81

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 535 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004908 (536 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5339

Human Homologs

Ensembl 110, assembly GRCh38.p14
reactive intermediate imine deaminase A homolog [Source:HGNC Symbol;Acc:HGNC:16897]
E-value: 8.0e-23
Percent Identity: 42.4

References

Two nifA-like genes required for expression of alternative nitrogenases by Azotobacter vinelandii.
Joerger RD, Jacobson MR, Bishop PE
J Bacteriol 1989 Jun;171(6):3258-67
PubMed ID: 2722750
Comparisons of Two Proteomic Analyses of Non-Mucoid and Mucoid Pseudomonas aeruginosa Clinical Isolates from a Cystic Fibrosis Patient.
Rao J, Damron FH, Basler M, Digiandomenico A, Sherman NE, Fox JW, Mekalanos JJ, Goldberg JB
Front Microbiol 2011;2:162
PubMed ID: 21863142