Pseudomonas aeruginosa PAO1, PA5356 (glcC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA5356
Name
glcC
Replicon chromosome
Genomic location 6023907 - 6024662 (+ strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_254043.1
GI 15600549
Affymetrix PA5356_glcC_at
DNASU PaCD00008319
Entrez 881632
GenBank AAG08741.1
INSDC AAG08741.1
NCBI Locus Tag PA5356
protein_id(GenBank) gb|AAG08741.1|AE004947_11|gnl|PseudoCAP|PA5356
TIGR NTL03PA05357
UniParc UPI00000C5FBF
UniProtKB Acc Q9HTK2
UniProtKB ID Q9HTK2_PSEAE
UniRef100 UniRef100_Q9HTK2
UniRef50 UniRef50_Q4KEF6
UniRef90 UniRef90_Q9HTK2

Product

Feature Type CDS
Coding Frame 1
Product Name
transcriptional regulator GlcC
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) 6.86
Kyte-Doolittle Hydrophobicity Value -0.567
Molecular Weight (kDa) 28.7
Isoelectric Point (pI) 9.90

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 387 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003745 (1397 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5356
Search term: glcC

Human Homologs

References

Cross-induction of glc and ace operons of Escherichia coli attributable to pathway intersection. Characterization of the glc promoter.
Pellicer MT, Fernandez C, Badía J, Aguilar J, Lin EC, Baldom L
J Biol Chem 1999 Jan 15;274(3):1745-52
PubMed ID: 9880556