Pseudomonas aeruginosa PAO1, PA5417 (soxD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA5417
Name
soxD
Replicon chromosome
Genomic location 6096707 - 6097027 (+ strand)
Transposon Mutants 5 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs
CommentStrains with transposon mutants in any of the soxBDAG genes are unable to grow on choline, glycine betaine, dimethylglcycine or sarcosine.

Cross-References

RefSeq NP_254104.1
GI 15600610
Affymetrix PA5417_soxD_at
DNASU PaCD00008340
Entrez 880061
GenBank AAG08802.1
INSDC AAG08802.1
NCBI Locus Tag PA5417
protein_id(GenBank) gb|AAG08802.1|AE004954_4|gnl|PseudoCAP|PA5417
TIGR NTL03PA05418
UniParc UPI00000C5FF4
UniProtKB Acc Q9HTE7
UniProtKB ID Q9HTE7_PSEAE
UniRef100 UniRef100_Q9HTE7
UniRef50 UniRef50_Q9HTE7
UniRef90 UniRef90_Q9HTE7

Product

Feature Type CDS
Coding Frame 1
Product Name
sarcosine oxidase delta subunit
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) -5.45
Kyte-Doolittle Hydrophobicity Value -0.615
Molecular Weight (kDa) 12.1
Isoelectric Point (pI) 5.48

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 72 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004971 (528 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5417
Search term: soxD

References

Sequence analysis of sarcosine oxidase and nearby genes reveals homologies with key enzymes of folate one-carbon metabolism.
Chlumsky LJ, Zhang L, Jorns MS
J. Biol. Chem. 1995 Aug;270(31):18252-9
PubMed ID: 7543100
Identification of two gene clusters and a transcriptional regulator required for Pseudomonas aeruginosa glycine betaine catabolism.
Wargo MJ, Szwergold BS, Hogan DA
J. Bacteriol. 2008 Apr;190(8):2690-9
PubMed ID: 17951379