Pseudomonas aeruginosa PAO1, PA5521

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA5521
Name
Replicon chromosome
Genomic location 6213581 - 6214339 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_254208.1
GI 15600714
Affymetrix PA5521_at
DNASU PaCD00008378
Entrez 879693
GenBank AAG08906.1
INSDC AAG08906.1
NCBI Locus Tag PA5521
protein_id(GenBank) gb|AAG08906.1|AE004964_9|gnl|PseudoCAP|PA5521
TIGR NTL03PA05522
UniParc UPI00000C6050
UniProtKB Acc Q9HT52
UniProtKB ID Q9HT52_PSEAE
UniRef100 UniRef100_W0Z0Z6
UniRef50 UniRef50_F6ACY1
UniRef90 UniRef90_W0Z0Z6

Product

Feature Type CDS
Coding Frame 1
Product Name
probable short-chain dehydrogenase
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -2.41
Kyte-Doolittle Hydrophobicity Value -0.039
Molecular Weight (kDa) 26.9
Isoelectric Point (pI) 5.77

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Cytoplasmic Class 2
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 651 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG005059 (355 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5521

Human Homologs

Ensembl 94, assembly GRCh38.p12
hydroxysteroid 17-beta dehydrogenase 8 [Source:HGNC Symbol;Acc:HGNC:3554]
E-value: 1.8e-19
Percent Identity: 30.2

References

Characterization of the p-toluenesulfonate operon tsaMBCD and tsaR in Comamonas testosteroni T-2.
Junker F, Kiewitz R, Cook AM
J. Bacteriol. 1997 Feb;179(3):919-27
PubMed ID: 9006050