Pseudomonas aeruginosa PAO1, PA5530

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA5530
Name
Replicon chromosome
Genomic location 6223174 - 6224481 (+ strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_254217.1
GI 15600723
Affymetrix PA5530_at
Entrez 878117
GenBank AAG08915.1
INSDC AAG08915.1
NCBI Locus Tag PA5530
protein_id(GenBank) gb|AAG08915.1|AE004965_7|gnl|PseudoCAP|PA5530
TIGR NTL03PA05531
UniParc UPI00000C6059
UniProtKB Acc Q9HT43
UniProtKB ID Q9HT43_PSEAE
UniRef100 UniRef100_W0Z285
UniRef50 UniRef50_A0QR49
UniRef90 UniRef90_F6ADF4

Product

Feature Type CDS
Coding Frame 1
Product Name
C5-dicarboxylate transporter
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 6.59
Kyte-Doolittle Hydrophobicity Value 0.545
Molecular Weight (kDa) 47.8
Isoelectric Point (pI) 9.08

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 2
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 359 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG005063 (498 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5530

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Genetic analysis of the assimilation of C5-dicarboxylic acids in Pseudomonas aeruginosa PAO1.
Lundgren BR, Villegas-Peñaranda LR, Harris JR, Mottern AM, Dunn DM, Boddy CN, Nomura CT
J Bacteriol 2014 Jul;196(14):2543-51
PubMed ID: 24794562