Pseudomonas aeruginosa PAO1, PA5536 (dksA2)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA5536
Name
dksA2
Replicon chromosome
Genomic location 6229458 - 6229862 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_254223.1
GI 15600729
Affymetrix PA5536_at
DNASU PaCD00008384
Entrez 877722
GenBank AAG08921.1
INSDC AAG08921.1
NCBI Locus Tag PA5536
protein_id(GenBank) gb|AAG08921.1|AE004966_3|gnl|PseudoCAP|PA5536
TIGR NTL03PA05537
UniParc UPI00000C605E
UniProtKB Acc Q9HT38
UniProtKB ID Q9HT38_PSEAE
UniRef100 UniRef100_Q9HT38
UniRef50 UniRef50_Q9HT38
UniRef90 UniRef90_Q9HT38

Product

Feature Type CDS
Coding Frame 1
Product Name
DksA2
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) -6.57
Kyte-Doolittle Hydrophobicity Value -1.075
Molecular Weight (kDa) 16.0
Isoelectric Point (pI) 4.76

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4IJJ HYDROLASE 12/21/12 Structure of transcription factor DksA2 from Pseudomonas aeruginosa PSEUDOMONAS AERUGINOSA 3.25 X-RAY DIFFRACTION 99.3

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 384 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG005069 (543 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5536
Search term: dksA2
Search term: DksA2

References

Role of a Zn-independent DksA in Zn homeostasis and stringent response.
Blaby-Haas CE, Furman R, Rodionov DA, Artsimovitch I, de Crécy-Lagard V
Mol. Microbiol. 2011 Feb;79(3):700-15
PubMed ID: 21255113