Pseudomonas aeruginosa PAO1, PA0031 (betC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA0031
Name
betC
Replicon chromosome
Genomic location 33000 - 34511 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_248721.1
GI 15595229
Affymetrix PA0031_betC_at
Entrez 880657
GenBank AAG03421.1
INSDC AAG03421.1
NCBI Locus Tag PA0031
protein_id(GenBank) gb|AAG03421.1|AE004442_8|gnl|PseudoCAP|PA0031
TIGR NTL03PA00032
UniParc UPI00000C4EF5
UniProtKB Acc Q9I799
UniProtKB ID Q9I799_PSEAE
UniRef100 UniRef100_Q9I799
UniRef50 UniRef50_Q4KKQ0
UniRef90 UniRef90_A6UX93

Product

Feature Type CDS
Coding Frame 1
Product Name
choline sulfatase
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) -4.66
Kyte-Doolittle Hydrophobicity Value -0.431
Molecular Weight (kDa) 57.4
Isoelectric Point (pI) 6.55

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 273 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000031 (518 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0031
Search term: betC
Search term: choline sulfatase

Human Homologs

Ensembl 86, assembly GRCh38.p7
iduronate 2-sulfatase [Source:HGNC Symbol;Acc:HGNC:5389]
E-value: 1.0e-23
Percent Identity: 28.1

References

Presence of a gene encoding choline sulfatase in Sinorhizobium meliloti bet operon: choline-O-sulfate is metabolized into glycine betaine.
Osterås M, Boncompagni E, Vincent N, Poggi MC, Le Rudulier D
Proc. Natl. Acad. Sci. U.S.A. 1998 Sep;95(19):11394-9
PubMed ID: 9736747