Pseudomonas aeruginosa PAO1, PA0173

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0173
Name
Replicon chromosome
Genomic location 197011 - 198060 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_248863.1
GI 15595371
Affymetrix PA0173_at
Entrez 882256
GenBank AAG03563.1
INSDC AAG03563.1
NCBI Locus Tag PA0173
protein_id(GenBank) gb|AAG03563.1|AE004455_4|gnl|PseudoCAP|PA0173
TIGR NTL03PA00174
UniParc UPI00000C4F7C
UniProtKB Acc Q9I6V9
UniProtKB ID CHEB2_PSEAE
UniRef100 UniRef100_Q9I6V9
UniRef50 UniRef50_Q9I6V9
UniRef90 UniRef90_Q9I6V9

Product

Feature Type CDS
Coding Frame 1
Product Name
probable methylesterase
Product Name Confidence: Class 3
Synonyms response regulator for chemotaxis
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 3.60
Kyte-Doolittle Hydrophobicity Value 0.011
Molecular Weight (kDa) 37.3
Isoelectric Point (pI) 8.49

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 2
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 586 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000171 (823 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0173

Human Homologs

References

Nucleotide sequence corresponding to five chemotaxis genes in Escherichia coli.
Mutoh N, Simon MI
J Bacteriol 1986 Jan;165(1):161-6
PubMed ID: 3510184
Phosphorylation of three proteins in the signaling pathway of bacterial chemotaxis.
Hess JF, Oosawa K, Kaplan N, Simon MI
Cell 1988 Apr 8;53(1):79-87
PubMed ID: 3280143