Pseudomonas aeruginosa PAO1, PA0263 (hcpC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest
Locus Tag
PA0263
Name
hcpC
Replicon chromosome
Genomic location 297043 - 297561 (- strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 7 transposon mutants in orthologs

Cross-References

RefSeq NP_248954.1
GI 15595460
Affymetrix PA0263_hcpC_s_at
DNASU PaCD00006119
Entrez 880866
GenBank AAG03652.1
NCBI Locus Tag PA0263
protein_id(GenBank) gb|AAG03652.1|AE004464_5|gnl|PseudoCAP|PA0263
TIGR NTL03PA00264
UniProtKB Acc Q9HI36
UniProtKB ID MAJE_PSEAE

Product

Feature Type CDS
Coding Frame 1
Product Name
secreted protein Hcp
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) -5.88
Kyte-Doolittle Hydrophobicity Value -0.449
Molecular Weight (kDa) 19.1
Isoelectric Point (pI) 5.76

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 3
Additional evidence for subcellular localization

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
3HE1 structural genomics, unknown function 05/07/09 Secreted protein Hcp3 from Pseudomonas aeruginosa. PSEUDOMONAS AERUGINOSA 2.098 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 67 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000260 (1018 members)
Putative Inparalogs 2 predicted inparalogs
secreted protein Hcp (PA1512) 100.0% identity
secreted protein Hcp (PA5267) 100.0% identity

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0263
Search term: hcpC

References

Vibrio cholerae Hcp, a secreted protein coregulated with HlyA.
Williams SG, Varcoe LT, Attridge SR, Manning PA
Infect. Immun. 1996 Jan;64(1):283-9
PubMed ID: 8557353
Rhs elements comprise three subfamilies which diverged prior to acquisition by Escherichia coli.
Wang YD, Zhao S, Hill CW
J. Bacteriol. 1998 Aug;180(16):4102-10
PubMed ID: 9696756