Pseudomonas aeruginosa PAO1, PA0292 (aguA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA0292
Name
aguA
Replicon chromosome
Genomic location 328801 - 329907 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_248983.1
GI 15595489
Affymetrix PA0292_at
Entrez 879730
GenBank AAG03681.1
INSDC AAG03681.1
NCBI Locus Tag PA0292
protein_id(GenBank) gb|AAG03681.1|AE004467_3|gnl|PseudoCAP|PA0292
TIGR NTL03PA00293
UniParc UPI00000C4FE7
UniProtKB Acc Q9I6J9
UniProtKB ID AGUA_PSEAE
UniRef100 UniRef100_Q9I6J9
UniRef50 UniRef50_Q8GWW7
UniRef90 UniRef90_Q9I6J9

Product

Feature Type CDS
Coding Frame 1
Product Name
agmatine deiminase
Product Name Confidence: Class 1
Synonyms agmatine iminohydrolase
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -18.27
Kyte-Doolittle Hydrophobicity Value -0.495
Molecular Weight (kDa) 41.2
Isoelectric Point (pI) 4.59

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 220 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000289 (553 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0292
Search term: aguA

References

Molecular characterization and regulation of the aguBA operon, responsible for agmatine utilization in Pseudomonas aeruginosa PAO1.
Nakada Y, Jiang Y, Nishijyo T, Itoh Y, Lu CD
J. Bacteriol. 2001 Nov;183(22):6517-24
PubMed ID: 11673419