Pseudomonas aeruginosa PAO1, PA0327 (carP)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0327
Name
carP
Replicon chromosome
Genomic location 367457 - 368422 (+ strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249018.1
GI 15595524
Affymetrix PA0327_at
DNASU PaCD00006144
Entrez 879241
GenBank AAG03716.1
INSDC AAG03716.1
NCBI Locus Tag PA0327
protein_id(GenBank) gb|AAG03716.1|AE004470_10|gnl|PseudoCAP|PA0327
TIGR NTL03PA00328
UniParc UPI00000C500A
UniProtKB Acc Q9I6G4
UniProtKB ID Q9I6G4_PSEAE
UniRef100 UniRef100_W0YMR5
UniRef50 UniRef50_V9R437
UniRef90 UniRef90_A6UYC8

Product

Feature Type CDS
Coding Frame 1
Product Name
calcium-regulated beta-propeller protein CarP
Product Name Confidence: Class 1
Synonyms hypothetical protein
Evidence for Translation
Charge (pH 7) -9.30
Kyte-Doolittle Hydrophobicity Value -0.210
Molecular Weight (kDa) 36.2
Isoelectric Point (pI) 5.02

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 29 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000319 (527 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0327
Search term: carP

Human Homologs

References

Analysis of the Escherichia coli genome VI: DNA sequence of the region from 92.8 through 100 minutes.
Burland V, Plunkett G 3rd, Sofia HJ, Daniels DL, Blattner FR
Nucleic Acids Res 1995 Jun 25;23(12):2105-19
PubMed ID: 7610040
The Pseudomonas aeruginosa PAO1 Two-Component Regulator CarSR Regulates Calcium Homeostasis and Calcium-Induced Virulence Factor Production through Its Regulatory Targets CarO and CarP.
Guragain M, King MM, Williamson KS, Pérez-Osorio AC, Akiyama T, Khanam S, Patrauchan MA, Franklin MJ
J Bacteriol 2016 Jan 11;198(6):951-63
PubMed ID: 26755627