Pseudomonas aeruginosa PAO1, PA0330 (rpiA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA0330
Name
rpiA
Replicon chromosome
Genomic location 371162 - 371833 (- strand)

Cross-References

RefSeq NP_249021.1
GI 15595527
Affymetrix PA0330_rpiA_at
DNASU PaCD00006146
Entrez 882171
GenBank AAG03719.1
INSDC AAG03719.1
NCBI Locus Tag PA0330
protein_id(GenBank) gb|AAG03719.1|AE004471_2|gnl|PseudoCAP|PA0330
TIGR NTL03PA00331
UniParc UPI00000C500D
UniProtKB Acc Q9I6G1
UniProtKB ID RPIA_PSEAE
UniRef100 UniRef100_B7V2P3
UniRef50 UniRef50_Q8PH49
UniRef90 UniRef90_B7V2P3

Product

Feature Type CDS
Coding Frame 1
Product Name
ribose 5-phosphate isomerase
Product Name Confidence: Class 2
Synonyms ribose 5-phosphate epimerase
phosphoriboisomerase
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -5.59
Kyte-Doolittle Hydrophobicity Value 0.137
Molecular Weight (kDa) 23.7
Isoelectric Point (pI) 5.32

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4X84 ISOMERASE 12/10/14 Crystal structure of Ribose-5-phosphate isomerase A from Pseudomonas aeruginosa PSEUDOMONAS AERUGINOSA 1.25 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 374 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000322 (552 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0330
Search term: rpiA

References

The tdh and serA operons of Escherichia coli: mutational analysis of the regulatory elements of leucine-responsive genes.
Rex JH, Aronson BD, Somerville RL
J. Bacteriol. 1991 Oct;173(19):5944-53
PubMed ID: 1917830
Escherichia coli rpiA gene encoding ribose phosphate isomerase A.
Hove-Jensen B, Maigaard M
J. Bacteriol. 1993 Sep;175(17):5628-35
PubMed ID: 8366047