Pseudomonas aeruginosa PAO1, PA0378

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest
Locus Tag
PA0378
Name
Synonym: mgtA
Replicon chromosome
Genomic location 422212 - 422943 (- strand)
Transposon Mutants 4 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249069.1
GI 15595575
Affymetrix PA0378_at
DNASU PaCD00006160
Entrez 879835
GenBank AAG03767.1
INSDC AAG03767.1
NCBI Locus Tag PA0378
protein_id(GenBank) gb|AAG03767.1|AE004475_9|gnl|PseudoCAP|PA0378
TIGR NTL03PA00379
UniParc UPI0000358915
UniProtKB Acc Q9I6B7
UniProtKB ID MTGA_PSEAE
UniRef100 UniRef100_Q9I6B7
UniRef50 UniRef50_Q9I6B7
UniRef90 UniRef90_Q9I6B7

Product

Feature Type CDS
Coding Frame 1
Product Name
probable transglycosylase
Product Name Confidence: Class 3
Synonyms monofunctional biosynthetic peptidoglycan transglycosylase
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 11.19
Kyte-Doolittle Hydrophobicity Value -0.159
Molecular Weight (kDa) 27.8
Isoelectric Point (pI) 10.86

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 552 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000369 (550 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0378

References

Monofunctional biosynthetic peptidoglycan transglycosylases.
Spratt BG, Zhou J, Taylor M, Merrick MJ
Mol. Microbiol. 1996 Feb;19(3):639-40
PubMed ID: 8830253