Pseudomonas aeruginosa PAO1, PA0400

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest
Locus Tag
PA0400
Name
Synonym: metB
Synonym: metC
Replicon chromosome
Genomic location 442008 - 443192 (+ strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 4 transposon mutants in orthologs

Cross-References

RefSeq NP_249091.1
GI 15595597
Affymetrix PA0400_at
Entrez 878286
GenBank AAG03789.1
INSDC AAG03789.1
NCBI Locus Tag PA0400
protein_id(GenBank) gb|AAG03789.1|AE004477_6|gnl|PseudoCAP|PA0400
TIGR NTL03PA00401
UniParc UPI00000C5042
UniProtKB Acc Q9I6A0
UniProtKB ID Q9I6A0_PSEAE
UniRef100 UniRef100_S0IXT8
UniRef50 UniRef50_Q8VCN5
UniRef90 UniRef90_A0A0A8RC28

Product

Feature Type CDS
Coding Frame 1
Product Name
probable cystathionine gamma-lyase
Product Name Confidence: Class 3
Synonyms cystine desulfhydrase
cystathionase
homoserine dehydratase
homoserine deaminase
cysteine desulfhydrase
gamma-cystathionase
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -2.75
Kyte-Doolittle Hydrophobicity Value -0.053
Molecular Weight (kDa) 42.8
Isoelectric Point (pI) 6.63

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Cytoplasmic Class 2
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 567 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000391 (869 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0400

Human Homologs

Ensembl 97, assembly GRCh38.p12
cystathionine gamma-lyase [Source:HGNC Symbol;Acc:HGNC:2501]
E-value: 5.5e-103
Percent Identity: 52.2

References

No references are associated with this feature.