Pseudomonas aeruginosa PAO1, PA0403 (pyrR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA0403
Name
pyrR
Replicon chromosome
Genomic location 445715 - 446227 (- strand)
Transposon Mutants 2 transposon mutants in PAO1

Cross-References

RefSeq NP_249094.1
GI 15595600
Affymetrix PA0403_pyrR_at
DNASU PaCD00006173
Entrez 878259
GenBank AAG03792.1
INSDC AAG03792.1
NCBI Locus Tag PA0403
protein_id(GenBank) gb|AAG03792.1|AE004477_9|gnl|PseudoCAP|PA0403
TIGR NTL03PA00404
UniParc UPI0000132E10
UniProtKB Acc Q9X6W6
UniProtKB ID PYRR_PSEAE
UniRef100 UniRef100_B7V3Z0
UniRef50 UniRef50_B7V3Z0
UniRef90 UniRef90_B7V3Z0

Product

Feature Type CDS
Coding Frame 1
Product Name
transcriptional regulator PyrR
Product Name Confidence: Class 2
Synonyms uracil phosphoribosyltransferase PyrR
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -3.07
Kyte-Doolittle Hydrophobicity Value -0.039
Molecular Weight (kDa) 18.7
Isoelectric Point (pI) 5.65

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 342 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000394 (553 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0403
Search term: pyrR

References

Two genes encoding uracil phosphoribosyltransferase are present in Bacillus subtilis.
Martinussen J, Glaser P, Andersen PS, Saxild HH
J. Bacteriol. 1995 Jan;177(1):271-4
PubMed ID: 7798145