Pseudomonas aeruginosa PAO1, PA0409 (pilH)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest
Locus Tag
PA0409
Name
pilH
Replicon chromosome
Genomic location 450093 - 450458 (+ strand)
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249100.1
GI 15595606
Affymetrix PA0409_pilH_at
Entrez 878198
GenBank AAG03798.1
INSDC AAG03798.1
NCBI Locus Tag PA0409
protein_id(GenBank) gb|AAG03798.1|AE004478_3|gnl|PseudoCAP|PA0409
TIGR NTL03PA00410
UniParc UPI0000131ACA
UniProtKB Acc P43501
UniProtKB ID PILH_PSEAE
UniRef100 UniRef100_P43501
UniRef50 UniRef50_P43501
UniRef90 UniRef90_P43501

Product

Feature Type CDS
Coding Frame 1
Product Name
twitching motility protein PilH
Product Name Confidence: Class 1
Synonyms type 4 fimbrial biogenesis protein PilH
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -2.53
Kyte-Doolittle Hydrophobicity Value -0.260
Molecular Weight (kDa) 13.3
Isoelectric Point (pI) 5.20

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Virulence Evidence

Source 1
Database VFDB : VF0082
Category Type IV pili twitching motility related proteins
Evidence
Host Organism
Notes
Reference 9224879

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 624 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000400 (553 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0409
Search term: pilH

References

Characterization of a Pseudomonas aeruginosa gene cluster involved in pilus biosynthesis and twitching motility: sequence similarity to the chemotaxis proteins of enterics and the gliding bacterium Myxococcus xanthus.
Darzins A
Mol. Microbiol. 1994 Jan;11(1):137-53
PubMed ID: 7908398
The molecular genetics of type-4 fimbriae in Pseudomonas aeruginosa--a review.
Mattick JS, Whitchurch CB, Alm RA
Gene 1996 Nov;179(1):147-55
PubMed ID: 8955641