Pseudomonas aeruginosa PAO1, PA0472 (fiuI)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0472
Name
fiuI
Synonym: fiuI
Replicon chromosome
Genomic location 533509 - 534027 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_249163.1
GI 15595669
Affymetrix PA0472_at
Entrez 880895
GenBank AAG03861.1
INSDC AAG03861.1
NCBI Locus Tag PA0472
protein_id(GenBank) gb|AAG03861.1|AE004485_2|gnl|PseudoCAP|PA0472
TIGR NTL03PA00473
UniParc UPI00000C5076
UniProtKB Acc Q9I646
UniProtKB ID Q9I646_PSEAE
UniRef100 UniRef100_W0YK06
UniRef50 UniRef50_O68593
UniRef90 UniRef90_O68593

Product

Feature Type CDS
Coding Frame 1
Product Name
FiuI
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) 0.65
Kyte-Doolittle Hydrophobicity Value -0.240
Molecular Weight (kDa) 19.5
Isoelectric Point (pI) 7.50

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 201 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000463 (1798 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0472
Search term: fiuI
Search term: FiuI

Human Homologs

References

Role for the outer membrane ferric siderophore receptor PupB in signal transduction across the bacterial cell envelope.
Koster M, van Klompenburg W, Bitter W, Leong J, Weisbeek P
EMBO J 1994 Jun 15;13(12):2805-13
PubMed ID: 8026465
Analysis of the Streptomyces coelicolor sigE gene reveals the existence of a subfamily of eubacterial RNA polymerase sigma factors involved in the regulation of extracytoplasmic functions.
Lonetto MA, Brown KL, Rudd KE, Buttner MJ
Proc Natl Acad Sci U S A 1994 Aug 2;91(16):7573-7
PubMed ID: 8052622
Gene repression by the ferric uptake regulator in Pseudomonas aeruginosa: cycle selection of iron-regulated genes.
Ochsner UA, Vasil ML
Proc Natl Acad Sci U S A 1996 Apr 30;93(9):4409-14
PubMed ID: 8633080
The heterologous siderophores ferrioxamine B and ferrichrome activate signaling pathways in Pseudomonas aeruginosa.
Llamas MA, Sparrius M, Kloet R, Jiménez CR, Vandenbroucke-Grauls C, Bitter W
J Bacteriol 2006 Mar;188(5):1882-91
PubMed ID: 16484199