Pseudomonas aeruginosa PAO1, PA0478

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest
Locus Tag
PA0478
Name
Replicon chromosome
Genomic location 539231 - 539707 (+ strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249169.1
GI 15595675
Affymetrix PA0478_at
DNASU PaCD00006199
Entrez 878613
GenBank AAG03867.1
INSDC AAG03867.1
NCBI Locus Tag PA0478
protein_id(GenBank) gb|AAG03867.1|AE004485_8|gnl|PseudoCAP|PA0478
TIGR NTL03PA00479
UniParc UPI00000C507B
UniProtKB Acc Q9I640
UniProtKB ID Q9I640_PSEAE
UniRef100 UniRef100_W0YLN6
UniRef50 UniRef50_A9AIE1
UniRef90 UniRef90_W0YLN6

Product

Feature Type CDS
Coding Frame 1
Product Name
probable N-acetyltransferase
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -5.83
Kyte-Doolittle Hydrophobicity Value -0.245
Molecular Weight (kDa) 18.1
Isoelectric Point (pI) 4.64

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
2FE7 STRUCTURAL GENOMICS, UNKNOWN FUNCTION 12/15/05 The crystal structure of a probable N-acetyltransferase from Pseudomonas aeruginosa PSEUDOMONAS AERUGINOSA UCBPP-PA14 2.0 X-RAY DIFFRACTION 99.4

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 274 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000467 (506 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0478

Human Homologs

Ensembl 97, assembly GRCh38.p12
spermidine/spermine N1-acetyltransferase family member 2 [Source:HGNC Symbol;Acc:HGNC:23160]
E-value: 2.4e-25
Percent Identity: 37.1

References

High specific induction of spermidine/spermine N1-acetyltransferase in a human large cell lung carcinoma.
Casero RA Jr, Celano P, Ervin SJ, Wiest L, Pegg AE
Biochem J 1990 Sep 15;270(3):615-20
PubMed ID: 2241897