Pseudomonas aeruginosa PAO1, PA0487

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0487
Name
Synonym: modR
Synonym: modE
Replicon chromosome
Genomic location 548468 - 549226 (- strand)
Transposon Mutants 5 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249178.1
GI 15595684
Affymetrix PA0487_at
DNASU PaCD00006202
Entrez 878638
GenBank AAG03876.1
INSDC AAG03876.1
NCBI Locus Tag PA0487
protein_id(GenBank) gb|AAG03876.1|AE004486_5|gnl|PseudoCAP|PA0487
TIGR NTL03PA00488
UniParc UPI00000C5083
UniProtKB Acc Q9I631
UniProtKB ID Q9I631_PSEAE
UniRef100 UniRef100_A0A071L798
UniRef50 UniRef50_D7I610
UniRef90 UniRef90_A0A071L798

Product

Feature Type CDS
Coding Frame 1
Product Name
probable molybdenum transport regulator
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 3.18
Kyte-Doolittle Hydrophobicity Value -0.037
Molecular Weight (kDa) 26.9
Isoelectric Point (pI) 9.17

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 213 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000476 (522 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0487

Human Homologs

References

Molecular analysis of the molybdate uptake operon, modABCD, of Escherichia coli and modR, a regulatory gene.
Walkenhorst HM, Hemschemeier SK, Eichenlaub R
Microbiol Res 1995 Nov;150(4):347-61
PubMed ID: 8564363
Characterisation of the molybdenum-responsive ModE regulatory protein and its binding to the promoter region of the modABCD (molybdenum transport) operon of Escherichia coli.
Anderson LA, Palmer T, Price NC, Bornemann S, Boxer DH, Pau RN
Eur J Biochem 1997 May 15;246(1):119-26
PubMed ID: 9210473