Pseudomonas aeruginosa PAO1, PA0572

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest
Locus Tag
PA0572
Name
Replicon chromosome
Genomic location 624994 - 627765 (- strand)
Transposon Mutants 4 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249263.1
GI 15595769
Affymetrix PA0572_at
Entrez 878237
GenBank AAG03961.1
INSDC AAG03961.1
NCBI Locus Tag PA0572
protein_id(GenBank) gb|AAG03961.1|AE004493_6|gnl|PseudoCAP|PA0572
TIGR NTL03PA00573
UniParc UPI00000C50C0
UniProtKB Acc Q9I5W4
UniProtKB ID Q9I5W4_PSEAE
UniRef100 UniRef100_Q9I5W4
UniRef50 UniRef50_Q9I5W4
UniRef90 UniRef90_Q9I5W4

Product

Feature Type CDS
Coding Frame 1
Product Name
hypothetical protein
Product Name Confidence: Class 4
Synonyms
Evidence for Translation
Detected by MALDI-TOF/TOF (PMID:19333994).
Charge (pH 7) -3.36
Kyte-Doolittle Hydrophobicity Value -0.337
Molecular Weight (kDa) 100.1
Isoelectric Point (pI) 6.52

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
Outer Membrane Class 3
Additional evidence for subcellular localization

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
5KDX HYDROLASE 06/08/16 IMPa metallopeptidase in complex with T-antigen PSEUDOMONAS AERUGINOSA (STRAIN ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228) 2.4 X-RAY DIFFRACTION 100.0
5KDW HYDROLASE 06/08/16 IMPa metallopeptidase from Pseudomonas aeruginosa PSEUDOMONAS AERUGINOSA (STRAIN ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228) 1.85 X-RAY DIFFRACTION 100.0
5KDV HYDROLASE 06/08/16 IMPa metallopeptidase from Pseudomonas aeruginosa PSEUDOMONAS AERUGINOSA (STRAIN ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228) 1.93 X-RAY DIFFRACTION 99.9

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 6 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000555 (302 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0572

References

Proteome analysis of extracellular proteins regulated by the las and rhl quorum sensing systems in Pseudomonas aeruginosa PAO1.
Nouwens AS, Beatson SA, Whitchurch CB, Walsh BJ, Schweizer HP, Mattick JS, Cordwell SJ
Microbiology 2003 May;149(Pt 5):1311-22
PubMed ID: 12724392
Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Analysis of the periplasmic proteome of Pseudomonas aeruginosa, a metabolically versatile opportunistic pathogen.
Imperi F, Ciccosanti F, Perdomo AB, Tiburzi F, Mancone C, Alonzi T, Ascenzi P, Piacentini M, Visca P, Fimia GM
Proteomics 2009 Apr;9(7):1901-15
PubMed ID: 19333994