Pseudomonas aeruginosa PAO1, PA0593 (pdxA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest
Locus Tag
PA0593
Name
pdxA
Replicon chromosome
Genomic location 651497 - 652483 (- strand)
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_249284.1
GI 15595790
Affymetrix PA0593_pdxA_at
Entrez 880733
GenBank AAG03982.1
INSDC AAG03982.1
NCBI Locus Tag PA0593
protein_id(GenBank) gb|AAG03982.1|AE004495_6|gnl|PseudoCAP|PA0593
TIGR NTL03PA00594
UniParc UPI0000132BA1
UniProtKB Acc Q9I5U4
UniProtKB ID PDXA1_PSEAE
UniRef100 UniRef100_Q9I5U4
UniRef50 UniRef50_Q9I5U4
UniRef90 UniRef90_Q9I5U4

Product

Feature Type CDS
Coding Frame 1
Product Name
pyridoxal phosphate biosynthetic protein PdxA
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -2.81
Kyte-Doolittle Hydrophobicity Value 0.121
Molecular Weight (kDa) 34.9
Isoelectric Point (pI) 6.62

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
1YXO OXIDOREDUCTASE 02/22/05 Crystal Structure of pyridoxal phosphate biosynthetic protein PdxA PA0593 PSEUDOMONAS AERUGINOSA 2.01 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 414 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000576 (553 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0593
Search term: pdxA

References

Overlap between pdxA and ksgA in the complex pdxA-ksgA-apaG-apaH operon of Escherichia coli K-12.
Roa BB, Connolly DM, Winkler ME
J Bacteriol 1989 Sep;171(9):4767-77
PubMed ID: 2670894