Pseudomonas aeruginosa PAO1, PA0601 (agtR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0601
Name
agtR
Replicon chromosome
Genomic location 662754 - 663386 (+ strand)
Transposon Mutants 1 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249292.1
GI 15595798
Affymetrix PA0601_at
Entrez 882060
GenBank AAG03990.1
INSDC AAG03990.1
NCBI Locus Tag PA0601
protein_id(GenBank) gb|AAG03990.1|AE004496_6|gnl|PseudoCAP|PA0601
TIGR NTL03PA00602
UniParc UPI00000C50D1
UniProtKB Acc Q9I5T7
UniProtKB ID Q9I5T7_PSEAE
UniRef100 UniRef100_W0YKW1
UniRef50 UniRef50_Q4K4Y4
UniRef90 UniRef90_A6UZA5

Product

Feature Type CDS
Coding Frame 1
Product Name
two-component response regulator, AgtR
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -1.59
Kyte-Doolittle Hydrophobicity Value 0.071
Molecular Weight (kDa) 22.9
Isoelectric Point (pI) 6.52

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 602 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000584 (519 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0601
Search term: agtR

Human Homologs

References

A complex network regulates expression of eps and other virulence genes of Pseudomonas solanacearum.
Huang J, Carney BF, Denny TP, Weissinger AK, Schell MA
J Bacteriol 1995 Mar;177(5):1259-67
PubMed ID: 7868600
Functional characterization of the agtABCD and agtSR operons for 4-aminobutyrate and 5-aminovalerate uptake and regulation in Pseudomonas aeruginosa PAO1.
Chou HT, Li JY, Lu CD
Curr Microbiol 2014 Jan;68(1):59-63
PubMed ID: 23982201