Pseudomonas aeruginosa PAO1, PA0603 (agtA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest
Locus Tag
PA0603
Name
agtA
Replicon chromosome
Genomic location 664783 - 665892 (+ strand)
Transposon Mutants 6 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_249294.1
GI 15595800
Affymetrix PA0603_at
Entrez 880619
GenBank AAG03992.1
INSDC AAG03992.1
NCBI Locus Tag PA0603
protein_id(GenBank) gb|AAG03992.1|AE004496_8|gnl|PseudoCAP|PA0603
TIGR NTL03PA00604
UniParc UPI00000C50D3
UniProtKB Acc Q9I5T5
UniProtKB ID Q9I5T5_PSEAE
UniRef100 UniRef100_W0YK72
UniRef50 UniRef50_B9KZG1
UniRef90 UniRef90_A0A024HBP3

Product

Feature Type CDS
Coding Frame 1
Product Name
AgtA
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -2.94
Kyte-Doolittle Hydrophobicity Value -0.146
Molecular Weight (kDa) 40.7
Isoelectric Point (pI) 6.43

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Cytoplasmic Membrane Class 2
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 669 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000586 (526 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0603
Search term: agtA
Search term: AgtA

Human Homologs

Ensembl 97, assembly GRCh38.p12
ATP binding cassette subfamily B member 4 [Source:HGNC Symbol;Acc:HGNC:45]
E-value: 1.7e-21
Percent Identity: 32.0

Human Homologs

Ensembl 97, assembly GRCh38.p12
ATP binding cassette subfamily B member 4 [Source:HGNC Symbol;Acc:HGNC:45]
E-value: 1.7e-21
Percent Identity: 32.0

Human Homologs

Ensembl 97, assembly GRCh38.p12
ATP binding cassette subfamily B member 4 [Source:HGNC Symbol;Acc:HGNC:45]
E-value: 1.7e-21
Percent Identity: 32.0

Human Homologs

Ensembl 97, assembly GRCh38.p12
ATP binding cassette subfamily B member 4 [Source:HGNC Symbol;Acc:HGNC:45]
E-value: 1.7e-21
Percent Identity: 32.0

References

Functional characterization of the agtABCD and agtSR operons for 4-aminobutyrate and 5-aminovalerate uptake and regulation in Pseudomonas aeruginosa PAO1.
Chou HT, Li JY, Lu CD
Curr. Microbiol. 2014 Jan;68(1):59-63
PubMed ID: 23982201