Pseudomonas aeruginosa PAO1, PA0651 (trpC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest
Locus Tag
PA0651
Name
trpC
Replicon chromosome
Genomic location 705130 - 705966 (+ strand)
Transposon Mutants 4 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249342.1
GI 15595848
Affymetrix PA0651_trpC_at
Entrez 882120
GenBank AAG04040.1
INSDC AAG04040.1
NCBI Locus Tag PA0651
protein_id(GenBank) gb|AAG04040.1|AE004500_6|gnl|PseudoCAP|PA0651
TIGR NTL03PA00652
UniParc UPI0000137557
UniProtKB Acc P20577
UniProtKB ID TRPC_PSEAE
UniRef100 UniRef100_P20577
UniRef50 UniRef50_P00911
UniRef90 UniRef90_P20577

Product

Feature Type CDS
Coding Frame 1
Product Name
indole-3-glycerol-phosphate synthase
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -11.35
Kyte-Doolittle Hydrophobicity Value 0.112
Molecular Weight (kDa) 30.3
Isoelectric Point (pI) 4.64

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 584 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000631 (553 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0651
Search term: trpC

References

DNA sequences and characterization of four early genes of the tryptophan pathway in Pseudomonas aeruginosa.
Essar DW, Eberly L, Han CY, Crawford IP
J Bacteriol 1990 Feb;172(2):853-66
PubMed ID: 2105306
Characterization of the indole-3-glycerol phosphate synthase from Pseudomonas aeruginosa PAO1.
Gerth ML, Nigon LV, Patrick WM
Protein J. 2012 Jun;31(5):359-65
PubMed ID: 22555873