Pseudomonas aeruginosa PAO1, PA0707 (toxR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA0707
Name
toxR
Synonym: regA
Replicon chromosome
Genomic location 780194 - 780973 (- strand)
Transposon Mutants 3 transposon mutants in PAO1

Cross-References

RefSeq NP_249398.1
GI 15595904
Affymetrix PA0707_toxR_at
DNASU PaCD00006323
Entrez 880684
GenBank AAG04096.1
INSDC AAA25981.1
NCBI Locus Tag PA0707
protein_id(GenBank) gb|AAG04096.1|AE004506_6|gnl|PseudoCAP|PA0707
TIGR NTL03PA00708
UniParc UPI000013718D
UniProtKB Acc P09852
UniProtKB ID TOXR_PSEAE
UniRef100 UniRef100_P09852
UniRef50 UniRef50_P09852
UniRef90 UniRef90_P09852

Product

Feature Type CDS
Coding Frame 1
Product Name
transcriptional regulator ToxR
Product Name Confidence: Class 1
Synonyms transcriptional regulator RegA
Evidence for Translation
Charge (pH 7) 2.16
Kyte-Doolittle Hydrophobicity Value -0.166
Molecular Weight (kDa) 28.9
Isoelectric Point (pI) 7.53

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 1
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in one genus

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000684 (302 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0707
Search term: toxR

References

Expression of the Pseudomonas aeruginosa toxA positive regulatory gene (regA) in Escherichia coli.
Hamood AN, Iglewski BH
J. Bacteriol. 1990 Feb;172(2):589-94
PubMed ID: 2105298
ToxR (RegA) activates Escherichia coli RNA polymerase to initiate transcription of Pseudomonas aeruginosa toxA.
Walker SL, Hiremath LS, Galloway DR
Gene 1995 Feb;154(1):15-21
PubMed ID: 7867943