Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA0740
|
Name |
sdsA1
Synonym: yjcS Synonym: sdsA1 |
Replicon | chromosome |
Genomic location | 806805 - 808781 (+ strand) |
Transposon Mutants | 2 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 1 transposon mutants in orthologs |
RefSeq | NP_249431.1 |
GI | 15595937 |
Affymetrix | PA0740_at |
Entrez | 882069 |
GenBank | AAG04129.1 |
INSDC | AAG04129.1 |
NCBI Locus Tag | PA0740 |
protein_id(GenBank) | gb|AAG04129.1|AE004509_4|gnl|PseudoCAP|PA0740 |
TIGR | NTL03PA00741 |
UniParc | UPI00000C512F |
UniProtKB Acc | Q9I5I9 |
UniProtKB ID | Q9I5I9_PSEAE |
UniRef100 | UniRef100_Q9I5I9 |
UniRef50 | UniRef50_Q9I5I9 |
UniRef90 | UniRef90_Q9I5I9 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
SDS hydrolase SdsA1
|
Synonyms |
SDS hydrolase SdsA1 (changed from probable beta-lactamase) |
Evidence for Translation | |
Charge (pH 7) | -8.84 |
Kyte-Doolittle Hydrophobicity Value | -0.252 |
Molecular Weight (kDa) | 72.6 |
Isoelectric Point (pI) | 5.82 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
2CG2 | HYDROLASE | 02/27/06 | Crystal structure of SdsA1, an alkylsulfatase from Pseudomonas aeruginosa, in complex with sulfate | PSEUDOMONAS AERUGINOSA | 2.1 | X-RAY DIFFRACTION | 100.0 |
2CFU | HYDROLASE | 02/23/06 | Crystal structure of SdsA1, an alkylsulfatase from Pseudomonas aeruginosa, in complex with 1-decane-sulfonic-acid. | PSEUDOMONAS AERUGINOSA | 1.9 | X-RAY DIFFRACTION | 100.0 |
2CG3 | HYDROLASE | 02/27/06 | Crystal structure of SdsA1, an alkylsulfatase from Pseudomonas aeruginosa. | PSEUDOMONAS AERUGINOSA | 2.6 | X-RAY DIFFRACTION | 100.0 |
5AJL | HYDROLASE | 02/25/15 | Sdsa sulfatase tetragonal | PSEUDOMONAS AERUGINOSA | 3.45 | X-RAY DIFFRACTION | 100.0 |
2CFZ | HYDROLASE | 02/26/06 | Crystal structure of SdsA1, an alkylsulfatase from Pseudomonas aeruginosa, in complex with 1-dodecanol | PSEUDOMONAS AERUGINOSA | 2.05 | X-RAY DIFFRACTION | 100.0 |
5AIJ | HYDROLASE | 02/13/15 | P. aeruginosa SdsA hexagonal polymorph | PSEUDOMONAS AERUGINOSA | 1.95 | X-RAY DIFFRACTION | 100.0 |
5A23 | HYDROLASE | 05/11/15 | SdsA sulfatase triclinic form | PSEUDOMONAS AERUGINOSA | 2.41 | X-RAY DIFFRACTION | 100.0 |
Identified by Diamond using e-value cutoff of 0.0001 and returning alignments that span 100% of the query sequence and that have more than 95% identity.
Drug Name | Source Accession | Source DB | Version | Target Accession | Target Description | Percent Identity | Alignment Length | E-Value |
1-DECANE-SULFONIC-ACID | DB06893 | DrugBank | 5.1.4 | Q9I5I9 | SDS hydrolase SdsA1 | 100.0 | 658 | 0.0e+00 |
1-DODECANOL | DB06894 | DrugBank | 5.1.4 | Q9I5I9 | SDS hydrolase SdsA1 | 100.0 | 658 | 0.0e+00 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 106 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG000715 (357 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA0740
Search term: sdsA1
Search term: SDS hydrolase SdsA1
|
The crystal structure of SdsA1, an alkylsulfatase from Pseudomonas aeruginosa, defines a third class of sulfatases.
Hagelueken G, Adams TM, Wiehlmann L, Widow U, Kolmar H, Tümmler B, Heinz DW, Schubert WD
Proc Natl Acad Sci U S A 2006 May 16;103(20):7631-6
PubMed ID: 16684886
|