Pseudomonas aeruginosa PAO1, PA0754

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0754
Name
Replicon chromosome
Genomic location 821902 - 822885 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249445.1
GI 15595951
Affymetrix PA0754_at
DNASU PaCD00006346
Entrez 882147
GenBank AAG04143.1
INSDC AAG04143.1
NCBI Locus Tag PA0754
protein_id(GenBank) gb|AAG04143.1|AE004510_7|gnl|PseudoCAP|PA0754
TIGR NTL03PA00755
UniParc UPI00000C513C
UniProtKB Acc Q9I5H5
UniProtKB ID Q9I5H5_PSEAE
UniRef100 UniRef100_W0YL14
UniRef50 UniRef50_C1DL48
UniRef90 UniRef90_A6VAM3

Product

Feature Type CDS
Coding Frame 1
Product Name
hypothetical protein
Product Name Confidence: Class 4
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -2.58
Kyte-Doolittle Hydrophobicity Value 0.029
Molecular Weight (kDa) 34.9
Isoelectric Point (pI) 5.46

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown (This protein may have multiple localization sites) Class 3
Unknown (This protein may have multiple localization sites) Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 182 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000728 (529 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0754

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Metabolic pathway for biosynthesis of poly(3-hydroxybutyrate-co-4-hydroxybutyrate) from 4-hydroxybutyrate by Alcaligenes eutrophus.
Valentin HE, Zwingmann G, Schönebaum A, Steinbüchel A
Eur J Biochem 1995 Jan 15;227(1-2):43-60
PubMed ID: 7851418