Pseudomonas aeruginosa PAO1, PA0836 (ackA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest
Locus Tag
PA0836
Name
ackA
Synonym: tdcD
Synonym: ackA
Replicon chromosome
Genomic location 911595 - 912779 (- strand)
Transposon Mutants 5 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249527.1
GI 15596033
Affymetrix PA0836_at
Entrez 877790
GenBank AAG04225.1
INSDC AAG04225.1
NCBI Locus Tag PA0836
protein_id(GenBank) gb|AAG04225.1|AE004518_6|gnl|PseudoCAP|PA0836
TIGR NTL03PA00837
UniParc UPI00000C517F
UniProtKB Acc Q9I5A4
UniProtKB ID ACKA_PSEAE
UniRef100 UniRef100_B7UYA0
UniRef50 UniRef50_Q9RR92
UniRef90 UniRef90_B7UYA0

Product

Feature Type CDS
Coding Frame 1
Product Name
acetate kinase
Product Name Confidence: Class 2
Synonyms acetate kinase
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 0.90
Kyte-Doolittle Hydrophobicity Value -0.068
Molecular Weight (kDa) 42.4
Isoelectric Point (pI) 7.10

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Cytoplasmic Class 2
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 439 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000804 (360 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0836
Search term: ackA
Search term: acetate kinase

References

Long-term anaerobic survival of the opportunistic pathogen Pseudomonas aeruginosa via pyruvate fermentation.
Eschbach M, Schreiber K, Trunk K, Buer J, Jahn D, Schobert M
J Bacteriol 2004 Jul;186(14):4596-604
PubMed ID: 15231792
Regulation of the Bacillus subtilis acetate kinase gene by CcpA.
Grundy FJ, Waters DA, Allen SH, Henkin TM
J. Bacteriol. 1993 Nov;175(22):7348-55
PubMed ID: 8226682
Novel keto acid formate-lyase and propionate kinase enzymes are components of an anaerobic pathway in Escherichia coli that degrades L-threonine to propionate.
Hesslinger C, Fairhurst SA, Sawers G
Mol. Microbiol. 1998 Jan;27(2):477-92
PubMed ID: 9484901