Pseudomonas aeruginosa PAO1, PA0930

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0930
Name
Synonym: pirS
Replicon chromosome
Genomic location 1016657 - 1017994 (+ strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249621.1
GI 15596127
Affymetrix PA0930_at
Entrez 878621
GenBank AAG04319.1
NCBI Locus Tag PA0930
protein_id(GenBank) gb|AAG04319.1|AE004527_6|gnl|PseudoCAP|PA0930
TIGR NTL03PA00931
UniProtKB Acc Q9I528
UniProtKB ID Q9I528_PSEAE

Product

Feature Type CDS
Coding Frame 1
Product Name
two-component sensor
Product Name Confidence: Class 2
Synonyms histidine protein kinase
Evidence for Translation
Charge (pH 7) 4.07
Kyte-Doolittle Hydrophobicity Value -0.158
Molecular Weight (kDa) 50.2
Isoelectric Point (pI) 8.36

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 614 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000896 (467 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0930

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Novel members of the two-component signal transduction genes in Escherichia coli.
Nagasawa S, Ishige K, Mizuno T
J Biochem 1993 Sep;114(3):350-7
PubMed ID: 8282725
Gene repression by the ferric uptake regulator in Pseudomonas aeruginosa: cycle selection of iron-regulated genes.
Ochsner UA, Vasil ML
Proc Natl Acad Sci U S A 1996 Apr 30;93(9):4409-14
PubMed ID: 8633080