Pseudomonas aeruginosa PAO1, PA0943

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0943
Name
Replicon chromosome
Genomic location 1031386 - 1032102 (- strand)
Transposon Mutants 1 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249634.1
GI 15596140
Affymetrix PA0943_at
DNASU PaCD00006431
Entrez 880898
GenBank AAG04332.1
INSDC AAG04332.1
NCBI Locus Tag PA0943
protein_id(GenBank) gb|AAG04332.1|AE004528_10|gnl|PseudoCAP|PA0943
TIGR NTL03PA00944
UniParc UPI00000C51CF
UniProtKB Acc Q9I515
UniProtKB ID Q9I515_PSEAE
UniRef100 UniRef100_Q9I515
UniRef50 UniRef50_G8Q5L8
UniRef90 UniRef90_Q9I515

Product

Feature Type CDS
Coding Frame 1
Product Name
hypothetical protein
Product Name Confidence: Class 4
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Detected by MALDI-TOF/TOF (PMID:19333994).
Charge (pH 7) 1.24
Kyte-Doolittle Hydrophobicity Value -0.496
Molecular Weight (kDa) 27.2
Isoelectric Point (pI) 8.67

Subcellular localization

Individual Mappings
Localization Confidence PMID
Periplasmic Class 3
Periplasmic Class 1
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 39 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000909 (536 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0943

Human Homologs

References

Analysis of secretin-induced stress in Pseudomonas aeruginosa suggests prevention rather than response and identifies a novel protein involved in secretin function.
Seo J, Brencic A, Darwin AJ
J Bacteriol 2009 Feb;191(3):898-908
PubMed ID: 19028883
Analysis of the periplasmic proteome of Pseudomonas aeruginosa, a metabolically versatile opportunistic pathogen.
Imperi F, Ciccosanti F, Perdomo AB, Tiburzi F, Mancone C, Alonzi T, Ascenzi P, Piacentini M, Visca P, Fimia GM
Proteomics 2009 Apr;9(7):1901-15
PubMed ID: 19333994