Pseudomonas aeruginosa PAO1, PA0993 (cupC2)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest
Locus Tag
PA0993
Name
cupC2
Replicon chromosome
Genomic location 1073960 - 1074673 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 4 transposon mutants in orthologs

Cross-References

RefSeq NP_249684.1
GI 15596190
Affymetrix PA0993_at
Entrez 878234
GenBank AAG04382.1
INSDC AAG04382.1
NCBI Locus Tag PA0993
protein_id(GenBank) gb|AAG04382.1|AE004532_6|gnl|PseudoCAP|PA0993
TIGR NTL03PA00994
UniParc UPI00000C51F5
UniProtKB Acc Q9I4X6
UniProtKB ID Q9I4X6_PSEAE
UniRef100 UniRef100_Q9I4X6
UniRef50 UniRef50_Q9I4X6
UniRef90 UniRef90_Q9I4X6

Product

Feature Type CDS
Coding Frame 1
Product Name
chaperone CupC2
Product Name Confidence: Class 2
Synonyms probable pili assembly chaperone
Evidence for Translation
Charge (pH 7) 7.47
Kyte-Doolittle Hydrophobicity Value -0.214
Molecular Weight (kDa) 25.7
Isoelectric Point (pI) 10.34

Subcellular localization

Individual Mappings
Localization Confidence PMID
Periplasmic Class 3
Periplasmic Class 2
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 54 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000956 (1752 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0993
Search term: cupC2
Search term: chaperone CupC2

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295