Pseudomonas aeruginosa PAO1, PA0998 (pqsC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA0998
Name
pqsC
Replicon chromosome
Genomic location 1080853 - 1081899 (+ strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs
CommentQuinolone signal response
Commentboth pqsC and pqsD are needed for quinolone signal biosynthesis

Cross-References

RefSeq NP_249689.1
GI 15596195
Affymetrix PA0998_at
DNASU PaCD00006461
Entrez 880660
GenBank AAG04387.1
INSDC AAG04387.1
NCBI Locus Tag PA0998
protein_id(GenBank) gb|AAG04387.1|AE004532_11|gnl|PseudoCAP|PA0998
TIGR NTL03PA00999
UniParc UPI00000C51FA
UniProtKB Acc Q9I4X1
UniProtKB ID Q9I4X1_PSEAE
UniRef100 UniRef100_W0YN16
UniRef50 UniRef50_W0YN16
UniRef90 UniRef90_W0YN16

Product

Feature Type CDS
Coding Frame 1
Product Name
PqsC
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -7.49
Kyte-Doolittle Hydrophobicity Value -0.050
Molecular Weight (kDa) 38.2
Isoelectric Point (pI) 4.86

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
6ET1 TRANSFERASE 10/25/17 Crystal structure of PqsBC from Pseudomonas aeruginosa (crystal form 2) PSEUDOMONAS AERUGINOSA PAO1 2.65 X-RAY DIFFRACTION 100.0
5DWZ TRANSFERASE 09/23/15 Structural and functional characterization of PqsBC, a condensing enzyme in the biosynthesis of the Pseudomonas aeruginosa quinolone signal PSEUDOMONAS AERUGINOSA 2.04 X-RAY DIFFRACTION 99.7
6ET3 TRANSFERASE 10/25/17 Crystal structure of PqsBC (C129S) mutant from Pseudomonas aeruginosa (crystal form 4) PSEUDOMONAS AERUGINOSA PAO1 2.25 X-RAY DIFFRACTION 99.7
6ET2 TRANSFERASE 10/25/17 Crystal structure of PqsBC (C129A) mutant from Pseudomonas aeruginosa (crystal form 3) PSEUDOMONAS AERUGINOSA PAO1 2.6 X-RAY DIFFRACTION 99.7
6ESZ TRANSFERASE 10/25/17 Crystal structure of PqsBC from Pseudomonas aeruginosa (crystal form 1) PSEUDOMONAS AERUGINOSA PAO1 1.84 X-RAY DIFFRACTION 100.0
6ET0 TRANSFERASE 10/25/17 Crystal structure of PqsBC (C129A) mutant from Pseudomonas aeruginosa (crystal form 1) PSEUDOMONAS AERUGINOSA PAO1 1.53 X-RAY DIFFRACTION 99.7

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 538 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000961 (300 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0998
Search term: pqsC
Search term: PqsC

References

No references are associated with this feature.