Pseudomonas aeruginosa PAO1, PA1017 (pauA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1017
Name
pauA
Replicon chromosome
Genomic location 1100930 - 1103077 (+ strand)
Transposon Mutants 4 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249708.1
GI 15596214
Affymetrix PA1017_pauA_at
Entrez 879355
GenBank AAG04406.1
INSDC AAG04406.1
NCBI Locus Tag PA1017
protein_id(GenBank) gb|AAG04406.1|AE004534_4|gnl|PseudoCAP|PA1017
TIGR NTL03PA01018
UniParc UPI00000C5206
UniProtKB Acc Q9I4V6
UniProtKB ID Q9I4V6_PSEAE
UniRef100 UniRef100_Q9I4V6
UniRef50 UniRef50_Q1LF00
UniRef90 UniRef90_A0A077JNC2

Product

Feature Type CDS
Coding Frame 1
Product Name
pimeloyl-CoA synthetase
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) -10.91
Kyte-Doolittle Hydrophobicity Value 0.177
Molecular Weight (kDa) 75.3
Isoelectric Point (pI) 5.26

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 375 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000979 (309 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1017
Search term: pauA

Human Homologs

References

Purification, characterization, DNA sequence and cloning of a pimeloyl-CoA synthetase from Pseudomonas mendocina 35.
Binieda A, Fuhrmann M, Lehner B, Rey-Berthod C, Frutiger-Hughes S, Hughes G, Shaw NM
Biochem J 1999 Jun 15;340 ( Pt 3)(Pt 3):793-801
PubMed ID: 10359666