Pseudomonas aeruginosa PAO1, PA1025 (opdD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1025
Name
opdD
Synonym: opdD
Replicon chromosome
Genomic location 1110947 - 1112197 (+ strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249716.1
GI 15596222
Affymetrix PA1025_at
DNASU PaCD00006470
Entrez 880285
GenBank AAG04414.1
INSDC AAG04414.1
NCBI Locus Tag PA1025
protein_id(GenBank) gb|AAG04414.1|AE004535_1|gnl|PseudoCAP|PA1025
TIGR NTL03PA01026
UniParc UPI00000C520D
UniProtKB Acc Q9I4U9
UniProtKB ID Q9I4U9_PSEAE
UniRef100 UniRef100_Q9I4U9
UniRef50 UniRef50_W6QYC2
UniRef90 UniRef90_Q9I4U9

Product

Feature Type CDS
Coding Frame 1
Product Name
OpdD
Product Name Confidence: Class 1
Synonyms Occk7
Evidence for Translation
Charge (pH 7) 0.41
Kyte-Doolittle Hydrophobicity Value -0.414
Molecular Weight (kDa) 46.5
Isoelectric Point (pI) 7.10

Subcellular localization

Individual Mappings
Localization Confidence PMID
Outer Membrane Class 3
Outer Membrane Class 2
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4FRT TRANSPORT PROTEIN 06/26/12 Crystal Structure of Pseudomonas aeruginosa OccK7 (OpdD) Pseudomonas aeruginosa 3.166 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 19 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000987 (294 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1025
Search term: opdD
Search term: OpdD

Human Homologs

References

Responses of carbapenemase-producing and non-producing carbapenem-resistant Pseudomonas aeruginosa strains to meropenem revealed by quantitative tandem mass spectrometry proteomics.
Salvà-Serra F, Jaén-Luchoro D, Marathe NP, Adlerberth I, Moore ERB, Karlsson R
Front Microbiol 2022;13:1089140
PubMed ID: 36845973
Role of the novel OprD family of porins in nutrient uptake in Pseudomonas aeruginosa.
Tamber S, Ochs MM, Hancock RE
J Bacteriol 2006 Jan;188(1):45-54
PubMed ID: 16352820
OccK channels from Pseudomonas aeruginosa exhibit diverse single-channel electrical signatures but conserved anion selectivity.
Liu J, Eren E, Vijayaraghavan J, Cheneke BR, Indic M, van den Berg B, Movileanu L
Biochemistry 2012 Mar 20;51(11):2319-30
PubMed ID: 22369314